Telomere shortening in sleep apnea syndrome
نویسندگان
چکیده
منابع مشابه
Oxidative Stress-induced Telomere Length Shortening of Circulating Leukocyte in Patients with Obstructive Sleep Apnea
The main mechanism of pathogenesis which causes systemic complications in obstructive sleep apnea (OSA) patients is believed to be intermittent hypoxia-induced intermediary effect and it depends on the burden of oxidative stress during sleep. We aimed to search the predictive markers which reflect the burden of systemic oxidative stress in patients with OSA and whether excessive telomere length...
متن کاملTelomere shortening, atherosclerosis, and metabolic syndrome.
This mechanism resembles inflammatory reactions to exogenous factors and the wound healing process (2). Dysfunction of vascular endothelial cells is thought to induce a cascade of pathologic reactions of cell groups mediated by the expression of adhesion molecules, resulting in infiltration of mononuclear cells, foam cell formation, promotion of thrombus formation, and disturbed relaxation of b...
متن کاملComplex Sleep Apnea Syndrome
Complex sleep apnea is the term used to describe a form of sleep disordered breathing in which repeated central apneas (>5/hour) persist or emerge when obstructive events are extinguished with positive airway pressure (PAP) and for which there is not a clear cause for the central apneas such as narcotics or systolic heart failure. The driving forces in the pathophysiology are felt to be ventila...
متن کامل[Obstructive sleep apnea syndrome].
This is an overview for the non-specialist of the pathophysiology, workup and treatment of the obstructive sleep apnea syndrome. The mechanisms leading to upper airway closure during sleep are discussed, as well as the current theoretical and experimental concepts for the apnea-induced arousal response and the consequent changes in sleep architecture and quality. Epidemiological data are summar...
متن کاملComplex sleep apnea syndrome
Complex sleep apnea syndrome (CompSAS) is a distinct form of sleep-disordered breathing characterized as central sleep apnea (CSA), and presents in obstructive sleep apnea (OSA) patients during initial treatment with a continuous positive airway pressure (CPAP) device. The mechanisms of why CompSAS occurs are not well understood, though we have a high loop gain theory that may help to explain i...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2010
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2010.03.025